Pathology Image Detail

Caption

Mammary gland, epithelial to mesenchymal transition: this photomicrograph illustrates areas with an epithelial phenotype (lower left portions of the photomicrograph) and their transition into a spindle cell carcinoma (upper left portions of the photomicrograph). Small clsuters and glands composed of cells with an epithelial phenotype are present in the areas composed of neoplastic spindle cells.

Description

Adenocarcinoma, solid, with epithelial to mesenchymal transition, mammary gland

Age at Necropsy

251 days

Contributor

Churchill GA (J:112750)

Pathologist

Mikaelian I (J:94320)

Method

H&E

Model

MMHC ID
MTB:29491
Tumor Name
Mammary gland • adenocarcinoma - solid
Treatment Type
None (spontaneous)
Tumor Synonyms
Adenocarcinoma, solid, with epithelial to mesenchymal transition, mammary gland
Organ Affected
Mammary gland
Frequency
observed
Reference
J:94320

Strain

Strain
FVB.Cg-Tg(WapMyc)212Bri/J
Strain Types
congenic
transgenic
General Note
Hemizygous mice. The genetic background of these mice was FVB/N. The transgene was originally generated on a (C57BL/6 x SJL)F2 background.
Strain Synonyms
FVB/N-Tg(WapMyc)212Bri/J
FVB-Myc
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
251 days