Pathology Image Detail

Caption	Mammary gland: this photomicrograph illustrates an areas of epithelial to mesenchymal transition. There is gradual transition between cords and solid areas of neoplastic cells with an epithelial phenotype to bundles of neoplastic cells with a spindloid (= mesenchymal) phenotype. The interstitium of the neoplasm is infiltrated by a moderate number of neutrophils.
Description	Carcinoma, solid, comedo, with squamous differentiation and epithelial to mesenchymal transition, mammary gland
Age at Necropsy	250 days
Contributor	Churchill GA (J:112750)
Pathologist	Mikaelian I (J:94320)
Method	H&E

Tumor Synonyms: Carcinoma, solid, comedo, with squamous differentiation and epithelial to mesenchymal transition, mammary gland

General Note: Hemizygous mice. The genetic background of these mice was FVB/N. The transgene was originally generated on a (C57BL/6 x SJL)F2 background.