Pathology Image Detail

Caption

639 day old male FVB/NJ mouse. The liver has multiple areas of various sizes in which the hepatic parenchyma is being replaced by large spindle-shaped cells, many of which have a golden brown pigment (hemosiderin) within their cytoplasm. In some areas these are clearly differentiating into vascular structures containing erythrocytes consistent with this being an hemangiosarcoma. Shows multiple foci.

Description

liver hemangiosarcoma

Age at Necropsy

639 days

Notes

639 day old male FVB/NJ mouse. The liver has multiple areas of various sizes in which the hepatic parenchyma is being replaced by large spindle-shaped cells, many of which have a golden brown pigment (hemosiderin) within their cytoplasm. In some areas these are clearly differentiating into vascular structures containing erythrocytes consistent with this being an hemangiosarcoma.

Contributor

Sundberg J (J:122261)

Pathologist

Sundberg J (J:122261)

Model

MMHC ID
MTB:31087
Tumor Name
Blood vessel • hemangiosarcoma
Treatment Type
None (spontaneous)
Tumor Synonyms
liver hemangiosarcoma
Organ Affected
Liver
Frequency
observed
Reference
J:122261

Strain

Strain
FVB/NJ
Strain Types
inbred
Strain Synonyms
FVB/J
FVB/N
WT
wild-type
wild-type FVB/NJ
FVB_NJ
FVB/Nj
FVB
Friend Virus B NIH Jackson
Strain Sex
Male
Reproductive Status
reproductive status not specified
Age of Detection
639 days