Pathology Image Detail

Caption

639 day old male FVB/NJ mouse. The liver has multiple areas of various sizes in which the hepatic parenchyma is being replaced by large spindle-shaped cells, many of which have a golden brown pigment (hemosiderin) within their cytoplasm. In some areas these are clearly differentiating into vascular structures containing erythrocytes consistent with this being an hemangiosarcoma. Higher magnification of a portion of the 2.5x image.

Description

liver hemangiosarcoma

Age at Necropsy

639 days

Notes

639 day old male FVB/NJ mouse. The liver has multiple areas of various sizes in which the hepatic parenchyma is being replaced by large spindle-shaped cells, many of which have a golden brown pigment (hemosiderin) within their cytoplasm. In some areas these are clearly differentiating into vascular structures containing erythrocytes consistent with this being an hemangiosarcoma.

Contributor

Sundberg J (J:122261)

Pathologist

Sundberg J (J:122261)

Model

MMHC ID
MTB:31087
Tumor Name
Blood vessel • hemangiosarcoma
Treatment Type
None (spontaneous)
Tumor Synonyms
liver hemangiosarcoma
Organ Affected
Liver
Frequency
observed
Reference
J:122261

Strain

Strain
FVB/NJ
Strain Types
inbred
Strain Synonyms
FVB/J
FVB/N
WT
wild-type
wild-type FVB/NJ
FVB_NJ
FVB/Nj
FVB
Friend Virus B NIH Jackson
Strain Sex
Male
Reproductive Status
reproductive status not specified
Age of Detection
639 days