Pathology Image Detail

Caption

This is a long bone from a 624 day old female KK/J mouse. The marrow cavity is filled with mature boney trabeculae and fibrovascular stroma resembling what Cory Brayton reports as fibrous osseous disease. This is a section of a femur.

Description

fibroosseus lesion

Age at Necropsy

624 days

Notes

This is a long bone from a 624 day old female KK/J mouse. The marrow cavity is filled with mature boney trabeculae and fibrovascular stroma resembling what Cory Brayton reports as fibrous osseous disease.

Contributor

Sundberg J (J:122261)

Pathologist

Sundberg J (J:122261)

Model

MMHC ID
MTB:31093
Tumor Name
Bone • lesion
Treatment Type
None (spontaneous)
Tumor Synonyms
fibrous osseous disease
fibroosseus lesion
Organ Affected
Bone
Frequency
observed
Reference
J:122261

Strain

Strain
KK/HlJ
Strain Types
inbred
General Note
Inbred strain. This strain is homozygous for Cdh23ahl, the age related hearing loss 1 mutation, which on this background results in progressive hearing loss with onset after 10 months of age.
Strain Synonyms
KK/J
KK/HiJ
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
624 days