Pathology Image Detail

Caption

This is the skin from a 624 day old KK/J female mouse. The neoplasm is a basal cell carcinoma with squamous metaplasia. High magnification reveals changes suggestive of tricholemma cornification forming abortive hair follicle-like structures. Image is a higher magnification of the center left portion of the 2.5x image.

Description

basal cell carcinoma

Age at Necropsy

624 days

Notes

This is the skin from a 624 day old KK/J female mouse. The neoplasm is a basal cell carcinoma with squamous metaplasia. High magnification reveals changes suggestive of tricholemma cornification forming abortive hair follicle-like structures.

Contributor

Sundberg J (J:122261)

Pathologist

Sundberg J (J:122261)

Model

MMHC ID
MTB:31098
Tumor Name
Skin - Epidermis - Basal cell • carcinoma
Treatment Type
None (spontaneous)
Tumor Synonyms
bsasal cell carcinoma
Organ Affected
Skin - Epidermis - Basal cell
Frequency
observed
Reference
J:122261

Strain

Strain
KK/HlJ
Strain Types
inbred
General Note
Inbred strain. This strain is homozygous for Cdh23ahl, the age related hearing loss 1 mutation, which on this background results in progressive hearing loss with onset after 10 months of age.
Strain Synonyms
KK/J
KK/HiJ
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
624 days