Pathology Image Detail

Caption

This is an adrenal gland from a 625 day old female BALB/cByJ mouse. The cortex (outer layer) should normally be uniform in thickness and tinctorial qualities. Thre are dark blue spindle cells proliferating (subcapsular cells) a common finding in mature and old mice. In addition there is a nodule of proliferating pale cells which are presumably an adrenal cortical adenoma. Immunohistochemistry will need to be done to determine which cell type is forming this lesion.

Description

adrenal cortical adenoma

Age at Necropsy

625 days

Notes

This is an adrenal gland from a 625 day old female BALB/cByJ mouse. The cortex (outer layer) should normally be uniform in thickness and tinctorial qualities. Thre are dark blue spindle cells proliferating (subcapsular cells) a common finding in mature and old mice. In addition there is a nodule of proliferating pale cells which are presumably an adrenal cortical adenoma. Immunohistochemistry will need to be done to determine which cell type is forming this lesion.

Contributor

Sundberg J (J:122261)

Pathologist

Sundberg J (J:122261)

Model

MMHC ID
MTB:31101
Tumor Name
Adrenal gland - Cortex • adenoma
Treatment Type
None (spontaneous)
Tumor Synonyms
adrenal cortical adenoma
Organ Affected
Adrenal gland - Cortex
Frequency
observed
Reference
J:122261

Strain

Strain
BALB/cByJ
Strain Types
inbred
Strain Synonyms
BALB Bailey
CBy
cBy
Balb/cByJ
BALB
BALB/c
BALB/c Bailey J
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
625 days