Pathology Image Detail

Caption

This is an adrenal gland from a 625 day old female BALB/cByJ mouse. The cortex (outer layer) should normally be uniform in thickness and tinctorial qualities. Thre are dark blue spindle cells proliferating (subcapsular cells) a common finding in mature and old mice. In addition there is a nodule of proliferating pale cells which are presumably an adrenal cortical adenoma. Immunohistochemistry will need to be done to determine which cell type is forming this lesion. Image is a higher magnification of the bottom left-center portion of the 4x image.

Description

adrenal cortical adenoma

Age at Necropsy

625 days

Notes

This is an adrenal gland from a 625 day old female BALB/cByJ mouse. The cortex (outer layer) should normally be uniform in thickness and tinctorial qualities. Thre are dark blue spindle cells proliferating (subcapsular cells) a common finding in mature and old mice. In addition there is a nodule of proliferating pale cells which are presumably an adrenal cortical adenoma. Immunohistochemistry will need to be done to determine which cell type is forming this lesion.

Contributor

Sundberg J (J:122261)

Pathologist

Sundberg J (J:122261)

Model

MMHC ID
MTB:31101
Tumor Name
Adrenal gland - Cortex • adenoma
Treatment Type
None (spontaneous)
Tumor Synonyms
adrenal cortical adenoma
Organ Affected
Adrenal gland - Cortex
Frequency
observed
Reference
J:122261

Strain

Strain
BALB/cByJ
Strain Types
inbred
Strain Synonyms
BALB Bailey
CBy
cBy
Balb/cByJ
BALB
BALB/c
BALB/c Bailey J
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
625 days