Caption |
These animals were injected with BrdUrd (10 mg/kg body weight) 1 h before death, and analysis of BrdUrd incorporation demonstrated a significantly higher S-phase fraction (P < 0.05 for three matched pairs) in the Rb+/-; ARF-/- sample (D) relative to the Rb+/- control (C). |
Description |
"Midsagittal section of pituitary tumors stained with BrdUrd showing 2.3 +/- 0.6% positive nuclei. Only low level of apoptosis observed by both TUNEL staining and study of H&E stained slides for hallmarks of apoptosis such as marginated chromatin and fragmented nuclei." |
Age at Necropsy |
6.5 month |
Notes |
Text and Fig 2c original source. |
Contributor |
Tsai KY (J:81016) |
Pathologist |
Tsai KY (J:81016) |
Copyright |
This image is from Tsai KY, Proc Natl Acad Sci USA 2002 Dec 24;99(26):16865-70. Copyright 2002 National Academy of Sciences, U.S.A. |
Method |
H&E |