Pathology Image Detail

Caption

 Note the strong Apc staining in the apical cytoplasm in the cells from the normal crypts (B, arrowhead). Higher magnification of A.

Description

 intestinal epithelial tumor

Notes

 See original reference Fig. 2A, B.

Contributor

 Shoemaker AR (J:49809)

Pathologist

 Shoemaker AR (J:49809)

Copyright

 This image is from Shoemaker AR, Proc Natl Acad Sci USA 1998 Sep 1;96(19):10826-31. Copyright 1998 National Academy of Sciences, U.S.A.
Image Probes

Type: antibody
Name
anti-Apc (3122)
Target
Apc
Notes
Rabbit polyclonal antibody 3122, raised against amino acids 8?347 of human APC

Model
MMHC ID
MTB:36361
Tumor Name
Intestine - Small Intestine • tumor
Treatment Type
None (spontaneous)
Tumor Synonyms
intestinal adenoma
Organ Affected
Intestine - Small Intestine
Frequency
observed
Reference
J:49809

Strain
Strain
AK.B6-ApcMin/+
Strain Types
chemically induced mutation
congenic
General Note
AKR/J mice congenic with the ApcMin locus from C57BL/6J.
Strain Synonyms
AKR Min/+
ApcMin/+
Strain Sex
Unspecified
Reproductive Status
reproductive status not specified