Pathology Image Detail

Caption

Apc staining is seen in normal crypts (C, arrowheads) and in the cells that encapsulate the tumor (C, arrow).

Description

intestinal epithelial tumor

Notes

See original reference Fig. 2C, D.

Contributor

Shoemaker AR (J:49809)

Pathologist

Shoemaker AR (J:49809)

Copyright

This image is from Shoemaker AR, Proc Natl Acad Sci USA 1998 Sep 1;96(19):10826-31. Copyright 1998 National Academy of Sciences, U.S.A.
Image Probes

Type: antibody

Name
anti-Apc (3122)
Target
Apc
Notes
Rabbit polyclonal antibody 3122, raised against amino acids 8?347 of human APC

Model

MMHC ID
MTB:36362
Tumor Name
Intestine - Small Intestine • tumor
Treatment Type
Chemical/Drug
Agent
[Agent] - Agent._Agent_key = [33] - Agent._AgentType_key = [3] - Agent.name = [1-ethyl-1-nitrosourea (ENU)] - Agent.description = [null] - Agent.create_user = [MTB] - Agent.create_date = [2005-01-05 13:31:30.0] - Agent.update_user = [dmk] - Agent.update_date = [2007-06-26 11:18:42.0]
Tumor Synonyms
intestine tumor
Organ Affected
Intestine - Small Intestine
Frequency
observed
Frequency Note
Sixteen-day-old mice were given a single i.p. injection of ENU (50?/g).
Reference
J:49809

Strain

Strain
AK.B6-ApcMin/+
Strain Types
chemically induced mutation
congenic
General Note
AKR/J mice congenic with the ApcMin locus from C57BL/6J.
Strain Synonyms
AKR Min/+
ApcMin/+
Strain Sex
Unspecified
Reproductive Status
reproductive status not specified