Pathology Image Detail

Caption	This is a 4x image stained with aldehyde fuschin.
Description	This is the pancreas and adjacent soft tissues from a 12 month old female KK/HiJ mouse. The pancreas is in the top of the field in the low magnification image. The tissue is stained with aldehyde fuschin to label beta cells that contain insulin (dark purple). The lower left half of the image contains two oval masses. The right one consists of white fat and amorphous pink material (coagulative necrosis of adipocytes). Although no stalk is evident in this section, this most likely was a pedunculated lipoma that underwent torsion of the stalk resulting in infarction of the lipoma.
Age at Necropsy	12 months
Contributor	Sundberg J (J:122261)
Pathologist	Sundberg J (J:122261)
Method	aldehyde fuschin

General Note: Inbred strain. This strain is homozygous for Cdh23ahl, the age related hearing loss 1 mutation, which on this background results in progressive hearing loss with onset after 10 months of age.