Pathology Image Detail

Caption

 The neoplasm contains areas of osteo-chondromatous (OC), neural (N), skeletal muscle (M) and epithelial (E) differentiation. The areas of osteo-chondromatous differentiation are associated with hematopoiesis. The areas of epithelial differentiation comprise tubular/glandular and solid portions.

Description

 Teratocarcinoma (malignant teratoma), extra-gonadal

Age at Necropsy

 35 days

Contributor

 Wu LC (J:94316)

Pathologist

 Mikaelian I (J:94314)

Method

 H&E

Model
MMHC ID
MTB:27563
Tumor Name
Germ cell (sex not specified) • teratocarcinoma
Treatment Type
None (spontaneous)
Tumor Synonyms
teratocarcinoma (malignant teratoma), extra-gonadal
Organ Affected
Germ cell (sex not specified)
Frequency
observed
Reference
J:94314

Strain
Strain
B6.129S6-Rag2tm1Fwa : 129X1/SvJ-Hivep3tm1Lcw
Strain Types
chimeric
targeted mutation (knockout)
General Note
Chimeric mice generated by injection of homozygous Hivep3-knockout ES cells into Rag2-deficient blastocysts.
Strain Synonyms
B6.129S6-Rag2tm1Fwa : 129X1/SvJ-Krctm1Lcw
KRC-/-;RAG2-/- chimera
Strain Sex
Unspecified
Reproductive Status
reproductive status not specified
Age of Detection
35 days