Pathology Image Detail

Caption

This portion of the neoplasm contains an island of cartilage with endochondral ossification (lower right corner), an epithelial structure with squamous differentiation and a prominent stratum granulosum (upper left corner), and an area of tubular differentiation (lower left corner). These structures are separated by areas of skeletal muscle differentiation composed of closely packed streaming bundles of fusiforms cells with eccentric nuclei.

Description

Teratocarcinoma (malignant teratoma), extra-gonadal

Age at Necropsy

35 days

Contributor

Wu LC (J:94316)

Pathologist

Mikaelian I (J:94314)

Method

H&E

Model

MMHC ID
MTB:27563
Tumor Name
Germ cell (sex not specified) • teratocarcinoma
Treatment Type
None (spontaneous)
Tumor Synonyms
teratocarcinoma (malignant teratoma), extra-gonadal
Organ Affected
Germ cell (sex not specified)
Frequency
observed
Reference
J:94314

Strain

Strain
B6.129S6-Rag2tm1Fwa : 129X1/SvJ-Hivep3tm1Lcw
Strain Types
chimeric
targeted mutation (knockout)
General Note
Chimeric mice generated by injection of homozygous Hivep3-knockout ES cells into Rag2-deficient blastocysts.
Strain Synonyms
B6.129S6-Rag2tm1Fwa : 129X1/SvJ-Krctm1Lcw
KRC-/-;RAG2-/- chimera
Strain Sex
Unspecified
Reproductive Status
reproductive status not specified
Age of Detection
35 days