Pathology Image Detail

Caption

A large island of chondromatous differentiation is surrounded by areas of epithelial differentiation. On the right lower corner, neoplastic cells for a dilated tubule lined by a one cell-thick ciliated epithelium reminiscent of the respiratory epithelium.

Description

Teratocarcinoma (malignant teratoma), extra-gonadal

Age at Necropsy

35 days

Contributor

Wu LC (J:94316)

Pathologist

Mikaelian I (J:94314)

Method

H&E

Model

MMHC ID
MTB:27563
Tumor Name
Germ cell (sex not specified) • teratocarcinoma
Treatment Type
None (spontaneous)
Tumor Synonyms
teratocarcinoma (malignant teratoma), extra-gonadal
Organ Affected
Germ cell (sex not specified)
Frequency
observed
Reference
J:94314

Strain

Strain
B6.129S6-Rag2tm1Fwa : 129X1/SvJ-Hivep3tm1Lcw
Strain Types
chimeric
targeted mutation (knockout)
General Note
Chimeric mice generated by injection of homozygous Hivep3-knockout ES cells into Rag2-deficient blastocysts.
Strain Synonyms
B6.129S6-Rag2tm1Fwa : 129X1/SvJ-Krctm1Lcw
KRC-/-;RAG2-/- chimera
Strain Sex
Unspecified
Reproductive Status
reproductive status not specified
Age of Detection
35 days