Pathology Image Detail

Caption

The neoplasm shows epithelial (left portion of the photomicrograph) and neural (right portion of the photomicrograph). An epithelial structure at the center of the photomicrograph is distended by a mucoid substance surrounded by a one cell-thick ciliated cuboidal epithelium reminiscent of the epithelium of the respiratory tract. Vacuolated cells may represent areas of chondromatous or lipomatous differentiation. Scattered areas of skeletal muscle are also present.

Description

Teratocarcinoma (malignant teratoma), extra-gonadal

Age at Necropsy

35 days

Contributor

Wu LC (J:94316)

Pathologist

Mikaelian I (J:94314)

Method

H&E

Model

MMHC ID
MTB:27563
Tumor Name
Germ cell (sex not specified) • teratocarcinoma
Treatment Type
None (spontaneous)
Tumor Synonyms
teratocarcinoma (malignant teratoma), extra-gonadal
Organ Affected
Germ cell (sex not specified)
Frequency
observed
Reference
J:94314

Strain

Strain
B6.129S6-Rag2tm1Fwa : 129X1/SvJ-Hivep3tm1Lcw
Strain Types
chimeric
targeted mutation (knockout)
General Note
Chimeric mice generated by injection of homozygous Hivep3-knockout ES cells into Rag2-deficient blastocysts.
Strain Synonyms
B6.129S6-Rag2tm1Fwa : 129X1/SvJ-Krctm1Lcw
KRC-/-;RAG2-/- chimera
Strain Sex
Unspecified
Reproductive Status
reproductive status not specified
Age of Detection
35 days