Pathology Image Detail

Caption

 This is a 2.5x image.

Description

 fibro-osseous lesion

Age at Necropsy

 427 days

Notes

 This is the vertebral body from a 427 day old female KK/H1J mouse. Note that most of the marrow cavity has been effaced by thick trabecular bone and fibrovascular stroma. This has been called "fibro-osseous lesion".

Contributor

 Sundberg J (J:122261)

Pathologist

 Sundberg J (J:122261)

Model
MMHC ID
MTB:50155
Tumor Name
Bone - Vertebral column - Vertebra • lesion - fibro-osseous
Treatment Type
None (spontaneous)
Tumor Synonyms
vertebral body fibro-osseous lesion
bone hyperplasia
Organ Affected
Bone - Vertebral column - Vertebra
Frequency
observed
Reference
J:122261

Strain
Strain
KK/HlJ
Strain Types
inbred
General Note
Inbred strain. This strain is homozygous for Cdh23ahl, the age related hearing loss 1 mutation, which on this background results in progressive hearing loss with onset after 10 months of age.
Strain Synonyms
KK/J
KK/HiJ
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
427 days