Pathology Image Detail

Caption

This is a 25x image, 25bx, that is a higher magnification of the center region of image 10bx.

Description

tail fibrosarcoma, nerve sheath tumor, spindle cell tumor

Age at Necropsy

451 days

Notes

This is the tail from a 451 day old female mouse. The mouse is an F2 hybrid from a cross between a C3H/HeJ female with alopecia areata and a C57BL/6J male. The mice in this study were used to dissect the genetic basis of alopecia areata. Background diseases were evaluated concurrently. This is a case of a locally extensive spindle cell tumor. It is most likely a fibrosarcoma but a differential diagnosis should include a nerve sheat tumor.

Contributor

Sundberg J (J:122261)

Pathologist

Sundberg J (J:122261)

Model

MMHC ID
MTB:54351
Tumor Name
PNS - Nerve sheath • tumor
Treatment Type
None (spontaneous)
Tumor Synonyms
tail fibrosarcoma
spindle cell tumor
nerve sheath tumor
Organ Affected
Tail
Frequency
observed
Reference
J:122261

Strain

Strain
C3B6F2
Strain Types
hybrid
General Note
The mouse is an F2 hybrid from a cross between a C3H/HeJ female with alopecia areata and a C57BL/6J male.
Strain Synonyms
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
451 days