Pathology Image Detail

Caption	This is a 40x image, 40bx, that is a higher magnification of the lower, middle center region of image 4ax.
Description	rhabdomyosarcoma
Age at Necropsy	652 days
Notes	This is a series of photomicrographs of a large invasive cancer found within skeletal muscles of a 652 day old AB6F2 mouse in an alopecia areata genetic study. This is a very aggressive and poorly differentiated rhabdomyoscaroma. Remnants of skeletal muscle cells are present, often with linear arrangements of nuclei. Mitotic index is relatively high. Many areas have poorly differentiated skeletal muscle cells. There are scattered areas of necrosis where the cancer has outgrown its blood supply.
Contributor	Sundberg J (J:122261)
Pathologist	Sundberg J (J:122261)

General Note: The mouse is an F2 hybrid from a cross between an A/J female with alopecia areata and a C57BL/6J male.