Caption |
This image was submitted by JM Ward. Image is from study set created by Herbert C. Morse III (NIAID, NIH), Torgny Fredrickson (NIAID, NIH), and Jerrold M. Ward (NCI, NIH) in 2001. A whole-slide scan image cane be viewed at https://images.jax.org/webclient/img_detail/15590. |
Description |
histiocyte-rich lymphoma |
Notes |
Diffuse large B-cell lymphoma, centroblastic, histiocyte-rich, spleen. There is diffuse infiltration of the spleen of a mixed population of tumor cells including large round blasts with large nucleoli, cells with irregular nuclei, and small round mature lymphocytes. Large eosinophilic histiocytic cells are found among the lymphoid cells. Foci of histiocytes contain pigmented vacuoles. Tumor cells are CD45R+ and non-non-neoplastic CD3+ infiltrating lymphocytes were seen. Repoterd CD45R and CD3 staining patterns have no submitted images. |
Contributor |
Ward JM (J:107304) |
Pathologist |
Ward JM (J:107304) |
Copyright |
This work was supported in part with funds from the Mouse Model of Cancers Consortium, National Cancer Institute, National Institutes of health, and by contract N01-C056000 from the National cancer Institute. |
Method |
H&E |
