Pathology Image Detail

Caption

 This image was submitted by John Sundberg, the Jackson Laboratory. This is a 4x image.

Description

 rear leg long bone fibro-osseous lesion

Age at Necropsy

 586 days

Notes

 This is a set of slides from a 586 day old female KK/HlJ mouse with fibro-osseous lesions of the long bones of the rear leg. The special stain exasserbates the bone and early areas of mineralization (blue).

Contributor

 Sundberg J (J:122261)

Pathologist

 Sundberg J (J:122261)

Method

 Mallory stain

Model
MMHC ID
MTB:70079
Tumor Name
Bone • hyperplasia
Treatment Type
None (spontaneous)
Tumor Synonyms
rear leg long bone fibro-osseus lesion
Organ Affected
Leg
Frequency
observed
Reference
J:122261

Strain
Strain
KK/HlJ
Strain Types
inbred
General Note
Inbred strain. This strain is homozygous for Cdh23ahl, the age related hearing loss 1 mutation, which on this background results in progressive hearing loss with onset after 10 months of age.
Strain Synonyms
KK/J
KK/HiJ
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
586 days