Pathology Image Detail

Caption	This image was submitted by John Sundberg, the Jackson Laboratory. This is a 25x image that is a higher magnification of the left-center, middle area of the 10x image.
Description	vertebra fibro-osseus lesion
Age at Necropsy	621 days
Notes	These are a series of photomicrographs of bones from various locations in a series of old mice to show relatively normal, mildly affected, to diffusely affected bones in which the marrow cavity is effaced by thick boney trabeculae. Between the trabeculae is a matrix of fibrovascular tissue sometimes containing variouis amounts of bone marrow. When present, the bone marrow is dominated by granulocytes.
Contributor	Sundberg J (J:122261)
Pathologist	Sundberg J (J:122261)
Method	H&E