Pathology Image Detail

Caption	This is a 25x image that is a higher magnification of the center area of the 4x image.
Description	long bone fibroosseous lesion
Age at Necropsy	586 days
Notes	This is a series of photomicrographs of fibroosseous lesion in the long bone of a 586 day old KK/H1J female mouse. The bones are stained with hematoxylin and eosin (pink and blue), sirius red (red and yellow), or immunohistochemistry for PBX1 expression.
Contributor	Sundberg J (J:122261)
Pathologist	Sundberg J (J:122261)
Method	Sirius Red

General Note: Inbred strain. This strain is homozygous for Cdh23ahl, the age related hearing loss 1 mutation, which on this background results in progressive hearing loss with onset after 10 months of age.