Pathology Image Detail

Caption

This is a 10x image stained for KRT10. This image is shown in Fig. 4C of the cited PLOS article.

Description

mildly hyperplastic epidermis

Notes

These are a series of normal skin tissue adjacent to trichoblastomas induced by a novel laboratory mouse papillomavirus (MmuPV1). This was a transmission study done in B6.Cg-Foxn1 (nude) mice. These images show different sections stained with H&E or adipophilin or antibodies for SOAT1, KRT1, KRT5, KRT6, KRT10, KRT14 or KRT17. Some of these images are also shown in Sundberg JP, PLOS ONE 2014; 10.1371/journal.pone.0113582.

Contributor

Sundberg J (J:94307)

Pathologist

Sundberg J (J:94307)

Copyright

This image was submitted by JP Sundberg, the Jackson Laboratory. This image is from Sundberg JP, PLOS ONE 2014; 10.1371/journal.pone.0113582, an open-access article distributed under the terms of the Creative Commons Attribution License.
Image Probes

Type: antibody

Name
anti-keratin 10 (PRB-159P)
Target
keratin 10 (mouse)
Supplier
Biolegend, formerlyCovance
Notes
rabbit polyclonal anti-mouse antibody

Model

MMHC ID
MTB:77227
Tumor Name
Skin • hyperplasia
Treatment Type
Virus
Agent
[Agent] - Agent._Agent_key = [735] - Agent._AgentType_key = [10] - Agent.name = [mouse papillomavirus (MmuPV1)] - Agent.description = [null] - Agent.create_user = [dab] - Agent.create_date = [2014-11-25 14:40:22.0] - Agent.update_user = [dab] - Agent.update_date = [2014-11-25 14:40:23.0]
Tumor Synonyms
mild skin hyperplasia
Organ Affected
Skin
Frequency
observed
Frequency Note
Mice were treated with mouse papillomavirus (MmuPV1).
Reference
J:94307

Strain

Strain
B6.Cg-Foxn1nu
Strain Types
congenic
spontaneous mutation
General Note
B6.Cg-Foxn1nu ("nude") mice with possible contribution from albino stock.
Strain Synonyms
B6.Cg-Foxn1 (nude)
Strain Sex
Female
Reproductive Status
reproductive status not specified