Pathology Image Detail

Caption

Mammary mass: the mammary gland is entirely effaced by a densely cellular, multilobular neoplastic process. Most lobules are separated by thick fibrovascular septae and are centered on cornified debris. One lobule is composed of delicate branching papillae supported by a small amount of fibrovascular stroma.

Description

Adenocarcinoma, secretory, with squamous differentiation, mammary gland

Age at Necropsy

254 days

Notes

The mouse had several tumors in its mammary glands and two macroscopic lung metastases when it was sacrificed. The mouse had undergone four cycles of gestation/lactation.

Contributor

Gallego MI (J:94332)

Pathologist

Mikaelian I (J:94320)

Method

H&E

Model

MMHC ID
MTB:24039
Tumor Name
Mammary gland • adenocarcinoma
Treatment Type
None (spontaneous)
Tumor Synonyms
mammary adenocarcinoma
adenocarcinoma, secretory, with squamous differentiation, mammary gland
mammary tumor
mammary carcinoma
Organ Affected
Mammary gland
Frequency
observed
Frequency Note
This tumor-bearing mouse had undergone four cycles of gestation and lactation.
Reference
J:94320

Strain

Strain
FVB/N-Tg(Wap-Hgf)402Mig
Strain Types
transgenic
Strain Synonyms
WAP-HGF
tg-HGF
line 402
Strain Sex
Female
Reproductive Status
multiparous
Age of Detection
254 days