Pathology Image Detail

Caption

Secretory mammary adenocarcinoma with squamous differentiation: this photomicrograph illustrates an area at the junction of the cornified epithelium and the glandular and solid portions of the neoplasm. The glandular portions become solid at the vicinity of the areas of cornification. Cornification is abrupt and results in the formation of rafts of ghost epithelial cells, a feature also observed in pilomatricomas.

Description

Adenocarcinoma, secretory, with squamous differentiation, mammary gland

Age at Necropsy

273 days

Notes

This mouse had undergone 4 cycles of gestation and lactation.

Contributor

Gallego MI (J:94332)

Pathologist

Mikaelian I (J:94320)

Method

H&E

Model

MMHC ID
MTB:24042
Tumor Name
Mammary gland • adenocarcinoma
Treatment Type
None (spontaneous)
Tumor Synonyms
mammary adenocarcinoma
adenocarcinoma, secretory, with squamous differentiation, mammary gland
mammary tumor
mammary carcinoma
Organ Affected
Mammary gland
Frequency
observed
Frequency Note
This tumor-bearing mouse had undergone four cycles of gestation and lactation.
Reference
J:94320

Strain

Strain
FVB/N-Tg(Wap-Hgf)402Mig
Strain Types
transgenic
Strain Synonyms
WAP-HGF
tg-HGF
line 402
Strain Sex
Female
Reproductive Status
multiparous
Age of Detection
273 days