Pathology Image Detail
Caption |
Secretory mammary adenocarcinoma with squamous differentiation: this photomicrograph illustrates an area of cornification. Neoplastic cells are arranged in nests, trabeculae and glands. Keratinization is abrupt and produces numerous large rafts of parakeratotic cells. The lumen of a gland (*) is filled with cornified debris intermingled with macrophages and desquamated neoplastic cells. Epithelial neoplastic structures are separated by a large amount of moderately inflamed fibrovascular stroma. |
Description |
Adenocarcinoma, secretory, with squamous differentiation, mammary gland |
Age at Necropsy |
334 days |
Notes |
The mouse had several tumors in its mammary glands and one macroscopic lung metastasis when it was sacrificed. The mouse had undergone four cycles of gestation/lactation. |
Contributor |
Gallego MI (J:94332) |
Pathologist |
Mikaelian I (J:94320) |
Method |
H&E |
Model |
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Strain |
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