Pathology Image Detail

Caption

Secretory mammary adenocarcinoma with squamous differentiation: this photomicrograph illustrates a portion of the neoplasm where neoplastic cells formed an epithelium resembling the epidermis. This epithelium undergoes squamous differentiation through a thin stratum granulosum and results into the production of numerous layers of keratin flakes.

Description

Adenocarcinoma, secretory, with squamous differentiation, mammary gland

Age at Necropsy

334 days

Notes

The mouse had several tumors in its mammary glands and one macroscopic lung metastasis when it was sacrificed. The mouse had undergone four cycles of gestation/lactation.

Contributor

Gallego MI (J:94332)

Pathologist

Mikaelian I (J:94320)

Method

H&E

Model

MMHC ID
MTB:24043
Tumor Name
Mammary gland • adenocarcinoma
Treatment Type
None (spontaneous)
Tumor Synonyms
mammary adenocarcinoma
adenocarcinoma, secretory, with squamous differentiation, mammary gland
mammary tumor
mammary carcinoma
Organ Affected
Mammary gland
Frequency
observed
Frequency Note
This tumor-bearing mouse had undergone four cycles of gestation and lactation.
Reference
J:94320

Strain

Strain
FVB/N-Tg(Wap-Hgf)402Mig
Strain Types
transgenic
Strain Synonyms
WAP-HGF
tg-HGF
line 402
Strain Sex
Female
Reproductive Status
multiparous
Age of Detection
334 days