Pathology Image Detail

Caption	Lung: the neoplastic epithelium is 2-6 cells-thick and shows keratinization that is either abrupt (as in a hair follicle) and which results into the formation of large rafts of parakeratotic cells, or that is associated with the formation of a layer of cells resembling the stratum granulosum of the epidermis and that is associated with the formation of lamellar cornified flakes. There is a prominent lymphocytic, plasmacytic and neutrophilic infiltrate at the periphery of the metastasis.
Description	Adenocarcinoma, secretory, with squamous differentiation, metastatic to the lung
Age at Necropsy	334 days
Notes	The mouse had several tumors in its mammary glands and one macroscopic lung metastasis when it was sacrificed. The mouse had undergone four cycles of gestation/lactation.
Contributor	Gallego MI (J:94332)
Pathologist	Mikaelian I (J:94320)
Method	H&E

Tumor Synonyms: Mammary adenocarcinoma, secretory, with squamous differentiation, metastatic, lung

Frequency Note: This tumor-bearing mouse had undergone four cycles of gestation and lactation.