Pathology Image Detail

Caption

Mammary gland: this photomicrograph is centered on an interlobular mammary duct which is markedly ectatic and contains an inspissated proteinaceous fluid. The epithelium has a crowded appearance and has an increased mitotic rate compared to a normal ductal epithelium. However, epithelial cells do not pile-up. There is mild perialveolar and periductal fibrosis and pleocellular inflammation.

Description

Hyperplasia and ductal ectasia, mammary gland

Age at Necropsy

254 days

Notes

The mouse had undergone four cycles of gestation/lactation.

Contributor

Gallego MI (J:94332)

Pathologist

Mikaelian I (J:94320)

Method

H&E

Model

MMHC ID
MTB:24046
Tumor Name
Mammary gland • hyperplasia
Treatment Type
None (spontaneous)
Tumor Synonyms
Hyperplasia and ductal ectasia, mammary gland
Organ Affected
Mammary gland
Frequency
observed
Frequency Note
This mouse had undergone four cycles of gestation and lactation.
Reference
J:94320

Strain

Strain
FVB/N-Tg(Wap-Hgf)402Mig
Strain Types
transgenic
Strain Synonyms
WAP-HGF
tg-HGF
line 402
Strain Sex
Female
Reproductive Status
multiparous
Age of Detection
254 days