Pathology Image Detail

Caption

 Mammary adenocarcinoma: there is weak cytoplasmic labeling for p21 of most neoplastic cells (antibody diluted at 1:100, tissues fixed Fekete's solution).

Description

 p21 immunohistochemistry, mammary adenocarcinoma

Age at Necropsy

 unknown

Contributor

 Mikaelian I (J:94320)

Pathologist

 Mikaelian I (J:94320)

Method

 IHC for p21
Image Probes

Type: antibody
Name
anti-p21 (F-5) (sc-6246)
Target
mouse p21
Supplier
Santa Cruz Biotechnology
Notes
"p21 (F-5) is provided as a mouse monoclonal IgG2b antibody corresponding to ... amino acids 1-159 representing full length p21 of mouse origin."

Model
MMHC ID
MTB:25429
Tumor Name
Mammary gland • adenocarcinoma
Treatment Type
None (spontaneous)
Tumor Synonyms
mammary adenocarcinoma
Organ Affected
Mammary gland
Frequency
observed
Reference
J:94320

Strain
Strain
B6SJL-Tg(Wnt1)1Hev/J
Strain Types
transgenic
General Note
The genetic background of this strain is approximately 50% C57BL/6 and 50% SJL. Mice are maintained by crossing transgene carriers to B6SJLF1 mice. Females are unable to lactate.
Strain Synonyms
B6SJL-Tg(Wnt1)1Hev
B6SJL-TgN(Wnt1)1Hev
B6SJL-Wnt1
B6SJL-Wnt1
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
unknown