Mouse Tumor Biology Database (MTB)
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Last Database Update
2019-09-15
MTB 3.0
 
HelpHelp and Documentation PDX Model Details
Model Details
Model ID:TM00026 Previous ID:BL0479F
Primary Site:Bladder Initial Diagnosis:Carcinoma: Urothelial carcinoma Final Diagnosis:bladder transitional cell carcinoma
Tumor Site:Bladder Tumor Type:Primary Malignancy Stage / Grade:pT2 / Grade:high
Patient
Sex:Female Age:78 Race / Ethnicity:White / Not Hispanic or Latino
Treatment Naive:No
Engraftment Host
Strain:NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ
(aka NSG or NOD Scid gamma)
Implantation Site: Sample Type:Surgical resection (fragment)
Publications citing this model
Tumor Mutation Burden
Sample from passage P1 has a TMB score of 14.54
TMB Range:0.81-305.22  (across all JAX PDX models)
TMB > 22 is considered high.
Variant Summary Help

Gene Expression Help Platforms:RNA_Seq, hu133, stRNA_Seq
Hatched bars indicate genes with expression levels determined to be mildly affected by alignment calculations. Details.
Gene CNV Help
CNV Plots Help
Model Characterization
Histology:

Patient tumor for PDX model TM00026.

P0 tumor for PDX model TM00026.
Circos Plots:

Circos plot