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Last Database Update
MTB 3.0
HelpHelp and Documentation PDX Model Details
Model Details
Model ID:TM00026 Previous ID:BL0479F
Primary Site:Bladder Initial Diagnosis:Carcinoma: Urothelial carcinoma Final Diagnosis:bladder transitional cell carcinoma
Tumor Site:Bladder Tumor Type:Primary Malignancy Stage / Grade:pT2 / Grade:high
Sex:Female Age:78 Race / Ethnicity:White / Not Hispanic or Latino
Treatment Naive:No
Engraftment Host
Strain:NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ
(aka NSG or NOD Scid gamma)
Implantation Site: Sample Type:Surgical resection (fragment)
Publications citing this model
Tumor Mutation Burden
Sample from passage P1 has a TMB score of 14.54
TMB Range:0.81-305.22  (across all JAX PDX models)
TMB > 22 is considered high.
Microsatellite Instability Help
Sample:BL0479F1895P0002P1     Score:MSI-S
Sample:BL0479F1895P0005P1     Score:MSI-S
Variant Summary Help

Gene Expression Help Platforms:RNA_Seq, hu133, stRNA_Seq
Hatched bars indicate genes with expression levels determined to be mildly affected by alignment calculations. Details.
Gene CNV Help
CNV Plots Help
Model Characterization

Patient tumor for PDX model TM00026.

P0 tumor for PDX model TM00026.
Circos Plots:

Circos plot