PDX Model DetailsTM00075

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PDX Model Summary
Model Details	Model ID (Previous ID) TM00075 (BN289F) Initial Diagnosis Brain glioblastoma multiforme Final Diagnosis Brain glioblastoma multiforme Stage/Grade Not Specified / Grade:IV Primary Site Brain Sample Site Brain Tumor Type Recurrent/Relapse
Patient	Sex Female Age (at time of tissue collection) 53 Race/Ethnicity Not Reported / Not Reported Treatment Naïve? Unknown Current Smoker/Former Smoker Unknown / Unknown
Engraftment	Host Strain NOD.Cg-Prkdc^scid Il2rg^tm1Wjl/SzJ (aka NSG or NOD Scid gamma) Sample Type Surgical resection (fragment) Engraftment Site no data

Molecular Data (Engrafted Tumor)
Variants	no variation plots
Gene Expression	Platforms: hu133, stRNA_Seq Hatched bars indicate genes with expression levels determined to be mildly affected by alignment calculations. Details.
Gene CNV	no CNV data
CNV Plots	no CNV plots
Tumor Mutation Burden	no data
Microsatellite Instability	no data
Gene Fusion	no data

Model Characterization

Histology

Summary:
P0, P1 pathology consistent with glioblastoma.
Pathologist:
Dr. Regina Gandour-Edwards, University of California, Davis.

Patient tumor for PDX model TM00075 stained for H&E.	P0 tumor F068 for PDX model TM00075 stained for H&E.
P0 tumor F068 ID023 for PDX model TM00075 stained for H&E.	P0 tumor F068 ID023 for PDX model TM00075 stained for GFAP. Staining was positive.
P0 tumor F068 ID023 for PDX model TM00075 stained for CD45. Staining was negative.

Dosing Studies

no data

Circos Plots

Circos plot for P0 tumor #068 for PDX model TM00075 (aka, BN289F)