Mouse Tumor Biology Database (MTB)
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Last Database Update
2019-09-15
MTB 3.0
 
HelpHelp and Documentation PDX Model Details
Model Details
Model ID:TM00219 Previous ID:LG1049F
Primary Site:Lung Initial Diagnosis:lung adenocarcinoma Final Diagnosis:lung adenocarcinoma
Tumor Site:Lymph node Tumor Type:Metastatic Stage / Grade:AJCC IV / Grade:1
Patient
Sex:Female Age:59 Race / Ethnicity:White / Not Hispanic or Latino
Treatment Naive:No
Engraftment Host
Strain:NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ
(aka NSG or NOD Scid gamma)
Implantation Site: Sample Type:Fine needle aspirate
Tumor Mutation Burden
Sample from passage P0 has a TMB score of 8.08
TMB Range:0.81-305.22  (across all JAX PDX models)
TMB > 22 is considered high.
Variant Summary Help

Gene Expression Help Platforms:RNA_Seq, hu133
Hatched bars indicate genes with expression levels determined to be mildly affected by alignment calculations. Details.
Gene CNV Help
CNV Plots Help
Model Characterization
Histology:

Patient tumor for PDX model TM00219; Fine needle aspirate

P0 tumor #1704 for PDX model TM00219.
Dosing Studies: