PDX Model DetailsTM00928

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PDX Model Summary

Model Details
Model ID (Previous ID)
TM00928 (LV1025F)
Initial Diagnosis
Adenocarcinoma
Final Diagnosis
Adenocarcinoma
Stage/Grade
AJCC IV / Grade:2
Primary Site
Colon
Sample Site
Liver
Tumor Type
Metastatic

Patient
Sex
Female
Age (at time of tissue collection)
no data
Race/Ethnicity
Not Reported / Not Reported
Treatment Naïve?
No
Current Smoker/Former Smoker
Unknown / Unknown

Engraftment
Host Strain
NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ
(aka NSG or NOD Scid gamma)
Sample Type
Surgical resection (fragment)
Engraftment Site
no data

Molecular Data (Engrafted Tumor)

Variants

Gene Expression

Platforms: RNA_Seq

Hatched bars indicate genes with expression levels determined to be mildly affected by alignment calculations. Details.

Gene CNV

CNV Plots

Tumor Mutation Burden

 no data

Microsatellite Instability

 no data

Gene Fusion

 no data

Model Characterization

Histology

 Summary:
P1 pathology consistent with colonic Adenocarcinoma.
Pathologist:
Dr. Regina Gandour-Edwards, University of California, Davis

P0 tumor F006P0 for PDX model TM00928 stained for H&E.
P0 tumor F006P0 for PDX model TM00928 stained for AE1/AE3. Staining was positive.

P0 tumor F006P0 for PDX model TM00928 stained for CD45. Staining was negative.
P1 tumor F006P0010P1 for PDX model TM00928 stained for H&E.

P1 tumor F006P0010P1 for PDX model TM00928 stained for AE1/AE3. Staining was positive
P1 tumor F006P0010P1 for PDX model TM00928 stained for CD45. Staining was negative

Dosing Studies

 no data

Circos Plots

 no data