PDX Model DetailsTM00977

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PDX Model Summary

Model Details
Model ID (Previous ID)
TM00977 (PA0277F)
Initial Diagnosis
Ampulla of Vater adenocarcinoma
Final Diagnosis
Ampulla of Vater adenocarcinoma
Stage/Grade
Not Specified /
Primary Site
Ampulla of Vater
Sample Site
Pancreas
Tumor Type
Primary Malignancy

Patient
Sex
Male
Age (at time of tissue collection)
76
Race/Ethnicity
White / Not Hispanic or Latino
Treatment Naïve?
Unknown
Current Smoker/Former Smoker
Unknown / Unknown

Engraftment
Host Strain
NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ
(aka NSG or NOD Scid gamma)
Sample Type
Surgical resection (fragment)
Engraftment Site
no data

Molecular Data (Engrafted Tumor)

Variants

Gene Expression

Platforms: RNA_Seq

Hatched bars indicate genes with expression levels determined to be mildly affected by alignment calculations. Details.

Gene CNV

CNV Plots

Tumor Mutation Burden

 no data

Microsatellite Instability

 no data

Gene Fusion

 no data

Model Characterization

Histology

 Summary:
P1 pathology consistent with pancreatic adenocarcinoma.
Pathologist:
Dr. Regina Gandour-Edwards, University of California, Davis

P1 tumor F091 ID36 for PDX model TM00977 stained for H&E.
P1 tumor F091 ID36 for PDX model TM00977 stained for AE1AE3. Staining was positive.

P1 tumor F091 ID36 for PDX model TM00977 stained for CD45. Staining was negative.
P1 tumor F091 ID36 for PDX model TM00977 stained for Ki67. Staining was positive.

Dosing Studies

 no data

Circos Plots

 no data