Reference SummaryFlaks A, Eur J Cancer 1968 Dec;4(6):579-85

Title

The susceptibility of various strains of neonatal mice to the carcinogenic effects of 9,10-dimethyl-1,2-benzanthracene.

Authors

Flaks A

Journal

Eur J Cancer

Volume

4

Issue

6

Year

1968

Pages

579-85

Abstract

Links

J:23487 – Mouse Genome Informatics
5717955 – National Library of Medicine/PubMed

Models

Strain Model Name Treatment Agent(s) Organ Affected Frequency Model Details
A/Flaks Connective tissue - Fibroblast fibrosarcoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Connective tissue - Fibroblast

7.7 - 9.1

C57BL Connective tissue - Fibroblast fibrosarcoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Connective tissue - Fibroblast

3.8 - 4.5

(A/Flaks x C57BL)F1 Connective tissue - Fibroblast fibrosarcoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Connective tissue - Fibroblast

3.8 - 9.1

(C57BL x A/Flaks)F1 Connective tissue - Fibroblast fibrosarcoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Connective tissue - Fibroblast

8 - 8.3

CBA Connective tissue - Fibroblast fibrosarcoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Connective tissue - Fibroblast

0 - 4.8

C3H Connective tissue - Fibroblast fibrosarcoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Connective tissue - Fibroblast

23 - 33

(CBA x C3H)F1 Connective tissue - Fibroblast fibrosarcoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Connective tissue - Fibroblast

4.2 - 7.7

(C3H x CBA)F1 Connective tissue - Fibroblast fibrosarcoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Connective tissue - Fibroblast

8 - 27

BALB/c Connective tissue - Fibroblast fibrosarcoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Connective tissue - Fibroblast

7.7 - 17

IF Connective tissue - Fibroblast fibrosarcoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Connective tissue - Fibroblast

4.8 - 8.3

(C3H x CBA)F1 Intestine carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Intestine

4

(CBA x C3H)F1 Kidney adenoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Kidney

3.8

(A/Flaks x C57BL)F1 Leukocyte - Lymphocyte lymphoma - small lymphocytic
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Leukocyte - Lymphocyte

4.5

A/Flaks Leukocyte leukemia Leukocyte

0

C57BL Leukocyte leukemia Leukocyte

0

(A/Flaks x C57BL)F1 Leukocyte leukemia Leukocyte

0

(C57BL x A/Flaks)F1 Leukocyte leukemia Leukocyte

0

CBA Leukocyte leukemia Leukocyte

0

C3H Leukocyte leukemia Leukocyte

0

(CBA x C3H)F1 Leukocyte leukemia Leukocyte

0

(C3H x CBA)F1 Leukocyte leukemia Leukocyte

0

BALB/c Leukocyte leukemia Leukocyte

0 - 14

IF Leukocyte leukemia Leukocyte

0

A/Flaks Leukocyte leukemia
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Leukocyte

0

C57BL Leukocyte leukemia
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Leukocyte

0 - 15

(A/Flaks x C57BL)F1 Leukocyte leukemia
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Leukocyte

38 - 59

(C57BL x A/Flaks)F1 Leukocyte leukemia
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Leukocyte

42 - 60

CBA Leukocyte leukemia
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Leukocyte

19 - 48

C3H Leukocyte leukemia
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Leukocyte

21 - 32

(CBA x C3H)F1 Leukocyte leukemia
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Leukocyte

23 - 37.5

(C3H x CBA)F1 Leukocyte leukemia
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Leukocyte

24 - 45

BALB/c Leukocyte leukemia
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Leukocyte

35 - 52

IF Leukocyte leukemia
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Leukocyte

12.5 - 29

C3H Liver hepatoma Liver

0 - 27

A/Flaks Liver hepatoma Liver

0

C57BL Liver hepatoma Liver

0

(A/Flaks x C57BL)F1 Liver hepatoma Liver

0

(C57BL x A/Flaks)F1 Liver hepatoma Liver

0

CBA Liver hepatoma Liver

3.7 - 15

(CBA x C3H)F1 Liver hepatoma Liver

0 - 24

(C3H x CBA)F1 Liver hepatoma Liver

8.8 - 19

BALB/c Liver hepatoma Liver

0

IF Liver hepatoma Liver

0

A/Flaks Liver hepatoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Liver

4.5 - 12

C57BL Liver hepatoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Liver

3.8 - 18

(A/Flaks x C57BL)F1 Liver hepatoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Liver

3.8 - 4.5

(C57BL x A/Flaks)F1 Liver hepatoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Liver

4.2 - 24

CBA Liver hepatoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Liver

36 - 52

C3H Liver hepatoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Liver

33 - 77

(CBA x C3H)F1 Liver hepatoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Liver

58 - 69

(C3H x CBA)F1 Liver hepatoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Liver

36 - 41

BALB/c Liver hepatoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Liver

0 - 12

IF Liver hepatoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Liver

8.3 - 14

A/Flaks Liver hepatoma - malignant
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Liver

0

C57BL Liver hepatoma - malignant
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Liver

0

(A/Flaks x C57BL)F1 Liver hepatoma - malignant
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Liver

0

(C57BL x A/Flaks)F1 Liver hepatoma - malignant
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Liver

0

CBA Liver hepatoma - malignant
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Liver

0 - 24

C3H Liver hepatoma - malignant
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Liver

0 - 4.5

(CBA x C3H)F1 Liver hepatoma - malignant
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Liver

0 - 23

(C3H x CBA)F1 Liver hepatoma - malignant
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Liver

0

BALB/c Liver hepatoma - malignant
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Liver

0

IF Liver hepatoma - malignant
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Liver

0

A/Flaks Lung adenoma Lung

13 - 23

A/Flaks Lung adenoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Lung

100

C57BL Lung adenoma Lung

0

(A/Flaks x C57BL)F1 Lung adenoma Lung

12 - 17

(C57BL x A/Flaks)F1 Lung adenoma Lung

8.8 - 13

CBA Lung adenoma Lung

0

C3H Lung adenoma Lung

0

(CBA x C3H)F1 Lung adenoma Lung

0

(C3H x CBA)F1 Lung adenoma Lung

0

BALB/c Lung adenoma Lung

1.7 - 5.3

IF Lung adenoma Lung

4 - 4.7

C57BL Lung adenoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Lung

0 - 3.8

(A/Flaks x C57BL)F1 Lung adenoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Lung

96 - 100

(C57BL x A/Flaks)F1 Lung adenoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Lung

100

CBA Lung adenoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Lung

64 - 67

C3H Lung adenoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Lung

50 - 64

(CBA x C3H)F1 Lung adenoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Lung

62.5 - 65

(C3H x CBA)F1 Lung adenoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Lung

23 - 56

BALB/c Lung adenoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Lung

92 - 100

IF Lung adenoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Lung

75 - 95

A/Flaks Lung carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Lung

32 - 42

C57BL Lung carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Lung

0

(A/Flaks x C57BL)F1 Lung carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Lung

7.7 - 14

(C57BL x A/Flaks)F1 Lung carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Lung

16 - 29

CBA Lung carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Lung

8 - 14

C3H Lung carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Lung

0 - 4.5

(CBA x C3H)F1 Lung carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Lung

0 - 7.7

(C3H x CBA)F1 Lung carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Lung

4 - 4.5

BALB/c Lung carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Lung

8.7 - 27

IF Lung carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Lung

0 - 4.8

A/Flaks Mammary gland carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Mammary gland

0

C57BL Mammary gland carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Mammary gland

0

(A/Flaks x C57BL)F1 Mammary gland carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Mammary gland

0

(C57BL x A/Flaks)F1 Mammary gland carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Mammary gland

0

CBA Mammary gland carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Mammary gland

0

C3H Mammary gland carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Mammary gland

0

(CBA x C3H)F1 Mammary gland carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Mammary gland

0

(C3H x CBA)F1 Mammary gland carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Mammary gland

8

BALB/c Mammary gland carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Mammary gland

0

IF Mammary gland carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Mammary gland

0

C3H Muscle - Striated - Skeletal rhabdomyosarcoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Muscle - Striated - Skeletal

8.3

BALB/c Muscle - Striated - Skeletal rhabdomyosarcoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Muscle - Striated - Skeletal

3.8

A/Flaks Ovary carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Ovary

3.8

C57BL Ovary carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Ovary

0

(A/Flaks x C57BL)F1 Ovary carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Ovary

7.7

(C57BL x A/Flaks)F1 Ovary carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Ovary

8.3

CBA Ovary carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Ovary

8

C3H Ovary carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Ovary

4.2

(CBA x C3H)F1 Ovary carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Ovary

12.5

(C3H x CBA)F1 Ovary carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Ovary

8

BALB/c Ovary carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Ovary

0

IF Ovary carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Ovary

8.3

BALB/c Salivary gland carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
Salivary gland

3.8

BALB/c (Unspecified organ) squamous cell carcinoma
  • 9,10-dimethyl-1,2-benzanthracene (DMBA)
(Unspecified organ)

8.7