Reference SummarySundberg JP, J Vet Diagn Invest 1992 Jul;4(3):312-7

Title

Forestomach papillomas in flaky skin and steel-Dickie mutant mice.

Authors

Sundberg JP; Kenty GA; Beamer WG; Adkison DL

Journal

J Vet Diagn Invest

Volume

4

Issue

3

Year

1992

Pages

312-7

Abstract

Gastric papillomas were diagnosed in flaky skin (fsn/fsn) and steel-Dickie (Sl/Sld) mutant mice but not littermate controls. Both mutants suffer from severe anemia of differing causes. Immunohistochemical screening and Southern blot analyses failed to detect any evidence of a papillomavirus in the gastric lesions. Phenotypic expression of the fsn and Sld mutant genes may play an essential role in the spontaneous development of forestomach papillomas in these mouse mutants.

Links

J:2777 – MGI References
1325193 – National Library of Medicine/PubMed

Strain Notes

Strain Note
CByJ.A-Ttc7fsn/J These mice were from The Jackson Laboratory.
WCB6F1/J-KitlSl/KitlSl-d These mice were from The Jackson Laboratory.

Models

Strain Model Name Treatment Agent(s) Organ Affected Frequency Model Details
CByJ.A-Ttc7fsn/J Forestomach papilloma Forestomach

observed

CBy.A/J Forestomach papilloma Forestomach

0

WCB6F1/J-KitlSl/KitlSl-d Forestomach papilloma Forestomach

observed

WCB6F1/J-KitlSl/+ Forestomach papilloma Forestomach

0

CByJ.A-Ttc7fsn/J Stomach - Glandular metaplasia - squamous Stomach - Glandular

observed