Strain SummaryC57BL/6-Kras^tm4Tyj/+ Ptf1a^{tm1.1(cre)Cvw}/+ Shoc2^tm1.1Mhan

Strain Name	C57BL/6-Kras^tm4Tyj/+ Ptf1a^{tm1.1(cre)Cvw}/+ Shoc2^tm1.1Mhan
Strain Type(s)	targeted mutation (conditional) • targeted mutation (knock-in)
Strain Synonym(s)	LSL-Kras^G12D;p48-Cre;Shoc2^fl/fl • KC-Shoc
Description	Heterozygous Kras, Ptf1a, homozygous Shoc2 mice on a C57BL/6 background with contribution from 129/SvJae, 129X1/SvJ, 129S1/Sv and 129S6/SvEvTac. All mice were back-crossed more than 6 times to C57BL/6 background.
Strain Genetics	List all models in MMHCdb carrying the Ptf1a^{tm1.1(cre)Cvw} allele Ptf1a^{tm1.1(cre)Cvw} / Ptf1a⁺
	List all models in MMHCdb carrying the Shoc2^tm1.1Mhan allele Shoc2^tm1.1Mhan / Shoc2^tm1.1Mhan
	List all models in MMHCdb carrying the Kras^tm4Tyj allele Kras^tm4Tyj / Kras⁺

Models
8 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Pancreas - Acinar cell metaplasia - ductal	Pancreas - Acinar cell					observed	References: Tan M, Cell Rep 2022 Dec 20;41(12):111837
Pancreas adenocarcinoma - ductal	Pancreas					0	References: Tan M, Cell Rep 2022 Dec 20;41(12):111837
Pancreas hyperplasia	Pancreas				0		References: Tan M, Cell Rep 2022 Dec 20;41(12):111837
Pancreas lesion - cystic	Pancreas					0	References: Tan M, Cell Rep 2022 Dec 20;41(12):111837
Pancreas pancreatic intraepithelial neoplasia 1 (PanIN1)	Pancreas					observed	References: Tan M, Cell Rep 2022 Dec 20;41(12):111837
Pancreas pancreatic intraepithelial neoplasia 2 (PanIN2)	PNS - Schwann cell					observed	References: Tan M, Cell Rep 2022 Dec 20;41(12):111837
Pancreas pancreatic intraepithelial neoplasia 2 (PanIN2)	Pancreas					observed	References: Tan M, Cell Rep 2022 Dec 20;41(12):111837
Pancreas pancreatic intraepithelial neoplasia 3 (PanIN3)	Pancreas					0 - observed	References: Tan M, Cell Rep 2022 Dec 20;41(12):111837

Models