Strain SummaryB6.Cg-Tg(RIP1-Tag)2Dh

Strain Name

 B6.Cg-Tg(RIP1-Tag)2Dh

Strain Type(s)

 congenic  •  transgenic

Strain Synonym(s)

 B6 RIP-Tag  •  C57Bl/6 RIP-Tag  •  C57BL/6-TgN(RIP1-Tag)2Dh  •  R1T2  •  R1T2B6  •  Rip1-Tag2  •  RIP1Tag2  •  RIP1-Tag2  •  RIP1-Tag2;B6  •  RIP1-Tag2/B6  •  RIP1-Tag2;C57B6/J  •  RIP-Tag  •  RIP-Tag2

Description

 This transgene was generated on a (C57BL/6J x DBA/2J)F2 genetic background. The genetic background of these mice is congenic C57BL/6.

Strain Genetics

 Tg(RIP1-Tag)2Dh

Models

15 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Pancreas - Islet of Langerhans - Beta cell adenoma Pancreas - Islet of Langerhans - Beta cell

very high

References: Bergers G, Nat Cell Biol 2000 Oct;2(10):737-44

Pancreas - Islet of Langerhans - Beta cell carcinoma Pancreas - Islet of Langerhans - Beta cell

very high

observed - 100

References: Bergers G, Nat Cell Biol 2000 Oct;2(10):737-44   ⋅   Hager JH, Cancer Res 2004 Apr 1;64(7):2406-10   ⋅   Hodgson G, Nat Genet 2001 Dec;29(4):459-64

Pancreas - Islet of Langerhans - Beta cell carcinoma in situ Pancreas - Islet of Langerhans - Beta cell

observed

References: Bergers G, Nat Cell Biol 2000 Oct;2(10):737-44

Pancreas - Islet of Langerhans - Beta cell dysplasia Pancreas - Islet of Langerhans - Beta cell

observed

References: Hager JH, Cancer Res 2004 Apr 1;64(7):2406-10

Pancreas - Islet of Langerhans - Beta cell hyperplasia Pancreas - Islet of Langerhans - Beta cell

100

observed

References: Bergers G, Nat Cell Biol 2000 Oct;2(10):737-44   ⋅   Christofori G, Nature 1994 Jun 2;369(6479):414-8   ⋅   Hager JH, Cancer Res 2004 Apr 1;64(7):2406-10   ⋅   Inoue M, Cancer Cell 2002 Mar;1(2):193-202

Pancreas - Islet of Langerhans - Beta cell hyperplasia Pancreas - Islet of Langerhans - Beta cell SU5416

very high

References: Bergers G, Nat Cell Biol 2000 Oct;2(10):737-44

Pancreas - Islet of Langerhans - Beta cell hyperplasia Pancreas - Islet of Langerhans - Beta cell batimastat (BB-94)

very high

References: Bergers G, Nat Cell Biol 2000 Oct;2(10):737-44

Pancreas - Islet of Langerhans - Beta cell hyperplasia Pancreas - Islet of Langerhans - Beta cell R94138

very high

References: Bergers G, Nat Cell Biol 2000 Oct;2(10):737-44

Pancreas - Islet of Langerhans - Beta cell tumor Pancreas - Islet of Langerhans - Beta cell

100

observed

References: Bergers G, Nat Cell Biol 2000 Oct;2(10):737-44   ⋅   Christofori G, Nature 1994 Jun 2;369(6479):414-8   ⋅   Inoue M, Cancer Cell 2002 Mar;1(2):193-202

Pancreas - Islet of Langerhans - Beta cell tumor Pancreas - Islet of Langerhans - Beta cell SU5416

very high

References: Bergers G, Nat Cell Biol 2000 Oct;2(10):737-44

Pancreas - Islet of Langerhans - Beta cell tumor Pancreas - Islet of Langerhans - Beta cell batimastat (BB-94)

very high

References: Bergers G, Nat Cell Biol 2000 Oct;2(10):737-44

Pancreas - Islet of Langerhans - Beta cell tumor Pancreas - Islet of Langerhans - Beta cell R94138

very high

References: Bergers G, Nat Cell Biol 2000 Oct;2(10):737-44

Pancreas - Islet of Langerhans hyperplasia Pancreas - Islet of Langerhans

observed

References: Ulanet DB, PLoS One 2010;5(8):e12454

Pancreas - Islet of Langerhans lesion - angiogenic Pancreas - Islet of Langerhans

observed

References: Ulanet DB, PLoS One 2010;5(8):e12454

Pancreas - Islet of Langerhans tumor Pancreas - Islet of Langerhans

observed

References: Ulanet DB, PLoS One 2010;5(8):e12454