Strain Summary129S7/SvEvBrd-Mt1^tm1Bri Mt2^tm1Bri/J

Strain Name	129S7/SvEvBrd-Mt1^tm1Bri Mt2^tm1Bri/J
Strain Type(s)	targeted mutation (knockout)
Strain Synonym(s)	129S7/SvEvBrd-Mt1^tm1Bri Mt2^tm1Bri • 129S7/SvEvBrd-Mt1^tm1Bri Mt2^tm1Bri/J • 129/SvEvBrd-Mt1^tm1Bri Mt2^tm1Bri • MT null • MT-null
Description	Homozygous mice. The Mt1 and Mt2 genes were targeted using a single construct.
Strain Links	• JAX Mice
Strain Genetics	List all models in MMHCdb carrying the Mt1^tm1Bri allele Mt1^tm1Bri / Mt1^tm1Bri
	List all models in MMHCdb carrying the Mt2^tm1Bri allele Mt2^tm1Bri / Mt2^tm1Bri

Models
3 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Urinary bladder transitional cell carcinoma	Urinary bladder	N-butyl-N-(4-hydroxybutyl)nitrosamine (BBN)				75	References: Kondo Y, Carcinogenesis 1999 Aug;20(8):1625-7
Urinary bladder transitional cell carcinoma	Urinary bladder	ZnCl2 ⋅ N-butyl-N-(4-hydroxybutyl)nitrosamine (BBN)				73	References: Kondo Y, Carcinogenesis 1999 Aug;20(8):1625-7
Urinary bladder tumor	Urinary bladder					0	References: Kondo Y, Carcinogenesis 1999 Aug;20(8):1625-7

Models