Strain SummaryB6;129P2-Il10^tm1Cgn

Strain Name	B6;129P2-Il10^tm1Cgn
Strain Type(s)	targeted mutation (knockout)
Strain Synonym(s)	IL-10^-/- • IL-10^-/- 129 X C57BL/6J • IL-10^-/- (C57BL/6 X 129Ola) • IL-10^-/- (C57BL/B6 X 129Ola)
Description	Homozygous mice. The genetic background of these mice is a mixture of C57BL/6J and 129P2/OlaHsd.
Strain Genetics	List all models in MMHCdb carrying the Il10^tm1Cgn allele Il10^tm1Cgn / Il10^tm1Cgn

Models
6 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Intestine - Large Intestine - Colon - Proximal adenocarcinoma	Intestine - Large Intestine - Colon - Proximal					observed	References: Berg DJ, J Clin Invest 1996 Aug 15;98(4):1010-20
Intestine - Large Intestine - Rectum adenocarcinoma	Intestine - Large Intestine - Rectum					observed	References: Berg DJ, J Clin Invest 1996 Aug 15;98(4):1010-20
Intestine - Large Intestine adenocarcinoma	Intestine - Large Intestine					0 - 67	References: Berg DJ, J Clin Invest 1996 Aug 15;98(4):1010-20 Sites of Metastasis: not Liver , not Lung , not Lymph node
Intestine - Large Intestine adenocarcinoma	Intestine - Large Intestine	anti-IFNgamma monoclonal antibody				0 - 29	References: Berg DJ, J Clin Invest 1996 Aug 15;98(4):1010-20
Intestine - Large Intestine adenocarcinoma	Intestine - Large Intestine	interleukin 10 (IL-10)				0 - 29	References: Berg DJ, J Clin Invest 1996 Aug 15;98(4):1010-20
Intestine - Large Intestine hyperplasia	Intestine - Large Intestine					observed	References: Berg DJ, J Clin Invest 1996 Aug 15;98(4):1010-20

Models