Strain SummaryFVBAF1-Tg(Trp53A135V)3Tgd

Strain Name	FVBAF1-Tg(Trp53A135V)3Tgd
Strain Type(s)	hybrid • transgenic
Strain Synonym(s)	FVBAF1-TgN(Trp53A135V)3Tgd • (FVB/N x A/J)F1-TgN(Trp53A135V)3Tgd • (FVB/N x A/J)F1-TgN(UL53)3Tgd • UL53-3 • (UL53-3 x A/J)F₁ p53^Val135/wt
Description	Hemizygous mice. FVB/N-Tg(Trp53A135V)3Tgd were crossed once to A/J mice.
Strain Genetics	List all models in MMHCdb carrying the Tg(Trp53A135V)3Tgd allele Tg(Trp53A135V)3Tgd

Models
8 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Lung adenoma	Lung				0 - 5.0		References: Zhang Z, Cancer Res 2000 Feb 15;60(4):901-7
Lung adenoma	Lung	N-methyl-N-nitrosourea (MNU)			100		References: Zhang Z, Cancer Res 2000 Feb 15;60(4):901-7
Lung adenoma	Lung	4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)			100		References: Zhang Z, Cancer Res 2000 Feb 15;60(4):901-7
Lung adenoma	Lung	benzo[a]pyrene (BP) (BaP) (B[a]P)			100		References: Zhang Z, Cancer Res 2000 Feb 15;60(4):901-7
Lung adenoma	Lung	4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) ⋅ dexamethasone (DEX) ⋅ myo-inositol			95		References: Zhang Z, Cancer Res 2000 Feb 15;60(4):901-7
Lung adenoma	Lung	4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) ⋅ green tea			100		References: Zhang Z, Cancer Res 2000 Feb 15;60(4):901-7
Lung adenoma	Lung	4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) ⋅ Taxol (paclitaxel)			100		References: Zhang Z, Cancer Res 2000 Feb 15;60(4):901-7
Lung adenoma	Lung	4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) ⋅ Adriamycin			100		References: Zhang Z, Cancer Res 2000 Feb 15;60(4):901-7

Models