Strain Summary[not specified]-Stk11tm1Mmt/+
Strain Name |
[not specified]-Stk11tm1Mmt/+ |
Strain Type(s) |
targeted mutation (knockout) |
Strain Synonym(s) |
Lkb1 (+/-) • Lkb1 heterozygous knockout • Lkb1+/- • Lkb1+/- |
Description |
Heterozygous mice. The genetic background was not specified. It contains 129X1/SvJ (from the ES cell of origin of the targeted mutant allele). |
Strain Genetics |
Stk11tm1Mmt / Stk11+ |
Frequency | ||||||||
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Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
Intestine - Small Intestine hamartoma | Intestine - Small Intestine |
observed |
0 - 46 |
References: Miyoshi H, Cancer Res 2002 Apr 15;62(8):2261-6 4 pathology image(s) |
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Liver hepatocellular carcinoma | Liver |
high |
References: Miyoshi H, Cancer Res 2002 Apr 15;62(8):2261-6 |
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Ovary tumor - stromal | Ovary |
0 |
References: Takeda H, Oncogene 2006 Mar 16;25(12):1816-20 |
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Stomach - Glandular hamartoma | Stomach - Glandular |
observed |
67 - 100 |
References: Miyoshi H, Cancer Res 2002 Apr 15;62(8):2261-6 6 pathology image(s) |
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Stomach hamartoma | Stomach |
0 - 100 |
0 - observed |
References: Miyoshi H, Cancer Res 2002 Apr 15;62(8):2261-6 ⋅ Takeda H, Br J Cancer 2004 Feb 9;90(3):701-4 ⋅ Takeda H, Oncogene 2006 Mar 16;25(12):1816-20 |
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Urinary bladder transitional cell papilloma | Urinary bladder |
0 |
References: Takeda H, Oncogene 2006 Mar 16;25(12):1816-20 |