Strain SummaryFVB.129S3-Nkx3-1tm1Mms
Strain Name |
FVB.129S3-Nkx3-1tm1Mms |
Strain Type(s) |
congenic • targeted mutation (knockout) |
Strain Synonym(s) |
FVB/N Nkx3.1-/- • Nkx3.1-/- |
Description |
Mice homozygous for a targeted mutation of Nkx3-1. Congenic animals were produced by 10 generations of sequential back-crosses. |
Strain Genetics |
Nkx3-1tm1Mms / Nkx3-1tm1Mms |
Frequency | ||||||||
---|---|---|---|---|---|---|---|---|
Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
Prostate gland - Epithelial cell hyperplasia | Prostate gland - Epithelial cell |
20 |
References: Kim MJ, Cancer Res 2002 Jun 1;62(11):2999-3004 |
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Prostate gland - Epithelial cell prostatic intraepithelial neoplasia (PIN) | Prostate gland - Epithelial cell |
80 |
References: Kim MJ, Cancer Res 2002 Jun 1;62(11):2999-3004 |