Strain SummaryB6;129-Stk11^tm1Mmt/+

Strain Name	B6;129-Stk11^tm1Mmt/+
Strain Type(s)	targeted mutation (knockout)
Strain Synonym(s)	Lkb1 (+/-) • Lkb1 +/- • Lkb1 heterozygote
Description	Heterozygous mice. The genetic background was a mix of C57BL/6, 129X1/SvJ, and possibly some other unspecified "129/Sv" substrain.
Strain Genetics	List all models in MMHCdb carrying the Stk11^tm1Mmt allele Stk11^tm1Mmt / Stk11⁺

Models
6 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Liver foci - acidophilic	Liver					observed	References: Nakau M, Cancer Res 2002 Aug 15;62(16):4549-53 3 pathology image(s)
Liver hepatoblastoma	Liver					observed	References: Nakau M, Cancer Res 2002 Aug 15;62(16):4549-53 1 pathology image(s)
Liver hepatocellular adenoma	Liver		0 - 100	14 - 100			References: Nakau M, Cancer Res 2002 Aug 15;62(16):4549-53
Liver hepatocellular carcinoma	Liver		0 - 33	0 - 75		observed	References: Nakau M, Cancer Res 2002 Aug 15;62(16):4549-53 Sites of Metastasis: Lung 3 pathology image(s)
Liver hepatocellular carcinoma - pseudoglandular	Liver					observed	References: Nakau M, Cancer Res 2002 Aug 15;62(16):4549-53 1 pathology image(s)
Liver hepatocellular carcinoma - trabecular	Liver					observed	References: Nakau M, Cancer Res 2002 Aug 15;62(16):4549-53 1 pathology image(s)

Models