Strain Summary[not specified]-Men1tm1.1Ctre/+

Strain Name

[not specified]-Men1tm1.1Ctre/+

Strain Type(s)

targeted mutation (knockout)

Strain Synonym(s)

conventional knockout  •  heterozygous Men1 knockout  •  Men1ΔN3-8/+

Description

The genetic background was not specified. It contained some 129S6/SvEvTac, possibly NIH Black Swiss, and likely some other strain as well.

Strain Genetics

Men1tm1.1Ctre / Men1+

Models

4 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Pancreas - Islet of Langerhans - Beta cell insulinoma Pancreas - Islet of Langerhans - Beta cell

observed

References: Crabtree JS, Mol Cell Biol 2003 Sep;23(17):6075-85

Pancreas - Islet of Langerhans adenoma Pancreas - Islet of Langerhans

83

References: Crabtree JS, Proc Natl Acad Sci U S A 2001 Jan 30;98(3):1118-23

Pancreas - Islet of Langerhans hyperplasia Pancreas - Islet of Langerhans

83

References: Crabtree JS, Proc Natl Acad Sci U S A 2001 Jan 30;98(3):1118-23

Pituitary gland adenoma Pituitary gland

observed

References: Crabtree JS, Mol Cell Biol 2003 Sep;23(17):6075-85