Strain SummaryC57BL/6-ApcMin/+ Cdkn1btm1Mlf
Strain Name |
C57BL/6-ApcMin/+ Cdkn1btm1Mlf |
Strain Type(s) |
chemically induced mutation • targeted mutation (knockout) |
Strain Synonym(s) |
B6.Cg-ApcMin/+ Cdkn1btm1Mlf • Min/+ p27-/- |
Description |
Mice were heterozygous for the ApcMin allele and homozygous for the Cdkn1btm1Mlf allele. These mice are the product of an intercross between strains on a predominantly C57BL/6 background. |
Strain Genetics |
ApcMin / Apc+ |
Pla2g2aMom1-s / Pla2g2aMom1-s | |
Cdkn1btm1Mlf / Cdkn1btm1Mlf |
Frequency | ||||||||
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Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
Intestine - Large Intestine - Colon tumor | Intestine - Large Intestine - Colon |
observed |
References: Philipp-Staheli J, Cancer Cell 2002 May;1(4):355-68 |
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Intestine - Small Intestine - Duodenum tumor | Intestine - Small Intestine - Duodenum |
observed |
References: Philipp-Staheli J, Cancer Cell 2002 May;1(4):355-68 |
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Intestine - Small Intestine - Ileum tumor | Intestine - Small Intestine - Ileum |
observed |
References: Philipp-Staheli J, Cancer Cell 2002 May;1(4):355-68 |
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Intestine - Small Intestine - Jejunum tumor | Intestine - Small Intestine - Jejunum |
observed |
References: Philipp-Staheli J, Cancer Cell 2002 May;1(4):355-68 |
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Intestine - Small Intestine adenoma | Intestine - Small Intestine |
observed |
References: Mikaelian I, Personal Communication 2004;(): 4 pathology image(s) |
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Intestine adenoma | Intestine |
observed |
References: Philipp-Staheli J, Cancer Cell 2002 May;1(4):355-68 |
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Intestine hyperplasia - adenomatous | Intestine |
observed |
References: Philipp-Staheli J, Cancer Cell 2002 May;1(4):355-68 |
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Intestine tumor | Intestine |
observed |
References: Philipp-Staheli J, Cancer Cell 2002 May;1(4):355-68 |