Strain SummaryC57BL/6-ApcMin/+ Cdkn1btm1Mlf

Strain Name

C57BL/6-ApcMin/+ Cdkn1btm1Mlf

Strain Type(s)

chemically induced mutation  •  targeted mutation (knockout)

Strain Synonym(s)

B6.Cg-ApcMin/+ Cdkn1btm1Mlf  •  Min/+ p27-/-

Description

Mice were heterozygous for the ApcMin allele and homozygous for the Cdkn1btm1Mlf allele. These mice are the product of an intercross between strains on a predominantly C57BL/6 background.

Strain Genetics

ApcMin / Apc+
Pla2g2aMom1-s / Pla2g2aMom1-s
Cdkn1btm1Mlf / Cdkn1btm1Mlf

Models

8 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon

observed

References: Philipp-Staheli J, Cancer Cell 2002 May;1(4):355-68

Intestine - Small Intestine - Duodenum tumor Intestine - Small Intestine - Duodenum

observed

References: Philipp-Staheli J, Cancer Cell 2002 May;1(4):355-68

Intestine - Small Intestine - Ileum tumor Intestine - Small Intestine - Ileum

observed

References: Philipp-Staheli J, Cancer Cell 2002 May;1(4):355-68

Intestine - Small Intestine - Jejunum tumor Intestine - Small Intestine - Jejunum

observed

References: Philipp-Staheli J, Cancer Cell 2002 May;1(4):355-68

Intestine - Small Intestine adenoma Intestine - Small Intestine

observed

References: Mikaelian I, Personal Communication 2004;():

4 pathology image(s)

Intestine adenoma Intestine

observed

References: Philipp-Staheli J, Cancer Cell 2002 May;1(4):355-68

Intestine hyperplasia - adenomatous Intestine

observed

References: Philipp-Staheli J, Cancer Cell 2002 May;1(4):355-68

Intestine tumor Intestine

observed

References: Philipp-Staheli J, Cancer Cell 2002 May;1(4):355-68