Strain Summary[not specified]-Brca1^tm1Cxd/Brca1^tm2Cxd Tg(KRT5-cre)5132Jlj

Strain Name	[not specified]-Brca1^tm1Cxd/Brca1^tm2Cxd Tg(KRT5-cre)5132Jlj
Strain Type(s)	targeted mutation (conditional) • targeted mutation (knockout) • transgenic
Strain Synonym(s)	K5 Cre:Brca1^co/- • [not specified]-Tg(KRT1-5-cre)5132Jlj Brca1^tm1Cxd/Brca1^tm2Cxd • [not specified]-Tg(KRT5-cre)1Jlj Brca1^tm1Cxd/Brca1^tm2Cxd • [not specified]-Tg(KRT5-cre)1Jlj Brca1^{tm1Cxd/tm2Cxd} • [not specified]-Tg(KRT5-cre)5132Jlj Brca1^tm1Cxd/Brca1^tm2Cxd
Description	Compound mutant mice. The genetic background of these mice included contributions from 129S6/SvEvTac, Black Swiss, and possibly C57BL/6 and other unspecified strains.
Strain Genetics	List all models in MMHCdb carrying the Brca1^tm1Cxd allele List all models in MMHCdb carrying the Brca1^tm2Cxd allele Brca1^tm1Cxd / Brca1^tm2Cxd
	List all models in MMHCdb carrying the Tg(KRT5-cre)5132Jlj allele Tg(KRT5-cre)5132Jlj

Models
16 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Ear - Inner ear carcinoma - basal	Ear - Inner ear				5.56		References: Berton TR, Oncogene 2003 Aug 21;22(35):5415-26
Ear squamous cell carcinoma	Ear				16.67		References: Berton TR, Oncogene 2003 Aug 21;22(35):5415-26
Ear tumor - epithelial	Ear				observed		References: Berton TR, Oncogene 2003 Aug 21;22(35):5415-26
Intestine - Small Intestine - Duodenum hyperplasia	Intestine - Small Intestine - Duodenum		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Leukocyte lymphoma	Leukocyte				5.56		References: Berton TR, Oncogene 2003 Aug 21;22(35):5415-26
Mesodermal cell/mesoblast sarcoma	Gastrointestinal tract				5.56		References: Berton TR, Oncogene 2003 Aug 21;22(35):5415-26
Mesodermal cell/mesoblast sarcoma - undifferentiated	Mesodermal cell/mesoblast				5.56		References: Berton TR, Oncogene 2003 Aug 21;22(35):5415-26
Mouth squamous cell carcinoma	Mouth				3.33		References: Berton TR, Oncogene 2003 Aug 21;22(35):5415-26
Mouth tumor - epithelial	Mouth				observed		References: Berton TR, Oncogene 2003 Aug 21;22(35):5415-26
Skin squamous cell carcinoma	Skin				22.22		References: Berton TR, Oncogene 2003 Aug 21;22(35):5415-26
Skin tumor - epithelial	Skin				observed		References: Berton TR, Oncogene 2003 Aug 21;22(35):5415-26
Uterus - Cervix tumor - epithelial	Uterus - Cervix		0				References: Berton TR, Oncogene 2003 Aug 21;22(35):5415-26
Vagina squamous cell carcinoma	Vagina				5.56		References: Berton TR, Oncogene 2003 Aug 21;22(35):5415-26
Vagina tumor - epithelial	Vagina		observed				References: Berton TR, Oncogene 2003 Aug 21;22(35):5415-26
(Unspecified organ) tumor	(Unspecified organ)				72.22		References: Berton TR, Oncogene 2003 Aug 21;22(35):5415-26
(Unspecified organ) tumor - epithelial	(Unspecified organ)				42.86		References: Berton TR, Oncogene 2003 Aug 21;22(35):5415-26