Strain SummaryB6;129S6-Rag2tm1Fwa
Strain Name |
B6;129S6-Rag2tm1Fwa |
Strain Type(s) |
targeted mutation (knockout) |
Strain Synonym(s) |
C57BL/6 Rag2 |
Description |
Mice were C57BL/6 (substrain not specified) with some contribution from 129S/SvEv-Gpi1c. Mice were homozygous for the Rag2tm1Fwa knockout. |
Strain Genetics |
Rag2tm1Fwa / Rag2tm1Fwa |
Frequency | ||||||||
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Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
Lung adenocarcinoma | Lung | Adenovirus - recombinant, expressing Jaagsiekte sheep retrovirus envelope protein ⋅ Adenovirus - recombinant, expressing human alkaline phosphatase |
observed |
References: Wootton SK, Nature 2005 Apr 14;434(7035):904-7 |
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Lung adenoma - papillary | Lung | Adenovirus - recombinant, expressing Jaagsiekte sheep retrovirus envelope protein ⋅ Adenovirus - recombinant, expressing human alkaline phosphatase |
observed |
References: Wootton SK, Nature 2005 Apr 14;434(7035):904-7 |
||||
Lung tumor | Lung | Adenovirus - recombinant, expressing Jaagsiekte sheep retrovirus envelope protein ⋅ Adenovirus - recombinant, expressing human alkaline phosphatase |
observed - 100 |
References: Wootton SK, Nature 2005 Apr 14;434(7035):904-7 |